Mainland Europe has the best access to Malta. Air Malta has flights between the main island and a host of other European cities. It also has flights between Malta and Cairo, Dubai, Damascus and Tunis. Other carriers with service to Malta include Alitalia, KLM, Lufthansa, Swissair and Tunisavia.

During summer, ferry service is available between Malta and Sicily and Genoa, Italy. The run between Malta and Catania (on Sicily) takes about three hours. All passengers departing by sea must pay a US$10 departure tax, plus a 15% government levy. Malta International Airport is located about 5km (3mi) southwest of Valletta. Buses, taxis and rental cars are available.

The public bus service on Malta and Gozo is a good way to get around. Buses on Malta serve the major tourist areas and on Gozo go practically everywhere.

Though Valletta and the Cottonera are easily explored on foot, renting a car is a good option if you want to get to the farther reaches of the island, especially as taxis are expensive. Major and local agencies are located on the main island. You can also rent motorcycles and bicycles on Malta. Driving is on the left.

Regular ferry service links Cirkewwa on Malta and Mgarr on Gozo, taking about 20 minutes each way. There's also irregular ferry service between each island and Comino. Check locally for schedules.